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and nucleocapsid proteins (which store its genetic material). Some vaccine-makers are looking to incorporate as many fragments as possible to increase the chances of having a broader immune response, while others are focusing on specific parts of the virus that seem to be conserved across each of the strains that have emerged so far. At Duke University, virologists are targeting a particular part of the spike protein known as the receptor binding domain (RBD), as this region appears to have relatively little variation between different forms of the same coronavirus.
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